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Onderzoeksprogramma I&W Biotechnologie en Veiligheid

Biotechnology is a highly dynamic field of research, with new developments occurring at a rapid pace. New DNA base pairs, interdisciplinary collaboration, and targeted changes to the genetic make-up of humans, animals and plants are producing many opportunities for innovation. In this context, it is important that the safety of these future uses and applications of biotechnology remain assured. The Dutch Ministry of Infrastructure and Water Management has therefore commissioned the research programme ‘Towards Modernisation of Biotechnology and Safety’. 
 
Goal
The main goal of the programme is to build scientific knowledge concerning the risks and uncertainties associated with state-of-the art and future modern biotechnology developments and applications, as well as to gain knowledge on ways to minimise and control those risks. As research on innovations does not automatically take into account the risks associated with them, the aim of this Programme is to stimulate the integration of risk research into current and future innovations in the field of modern biotechnology. The Programme will generate knowledge that can be used to further refine and develop the risk assessment and risk management system.
 
Two separate Calls for proposals were held
 
Call 1 (closed): Current Genetic Modification Techniques and Applications in relation to Safety
Call 2 (closed): New and Future Modern Biotechnology Techniques and Applications in relation to Environmental Safety
 
Information & Matchmaking event
To encourage the submission of proposals and formation of required partnerships, an Information & Matchmaking Event was organised on 15 September 2017. Part of the introduction to the Programme was provided by Dr. Todd Kuiken (North Carolina State University, USA) through 4 short films on the need for the Programme.
 
During the lively discussions a list of Frequently Asked Questions was compiled, together with answers. Please find them here.
 
The three presentations held during the event can be found below:
- STW
 
More information
More information about the programme can be found on the website of RIVM (in Dutch).
 
Documents
Below you can find the documents related to Deadline Call 2: New and Future Modern Biotechnology Techniques and Applications in relation to Environmental Safety.
 

Background literature for the Biotechnology and Safety Programme, Call 2

Financieringsinstrument 
Doel 
The main goal of the programme is to build scientific knowledge concerning the risks and uncertainties associated with state-of-the art and future modern biotechnology developments and applications, as well as to gain knowledge on ways to minimise and control those risks. As research on innovations does not automatically take into account the risks associated with them, the aim of this Programme is to stimulate the integration of risk research into current and future innovations in the field of modern biotechnology. The Programme will generate knowledge that can be used to further refine and develop the risk assessment and risk management system.
Begindatum 
2016
Einddatum 
2022
Bekijk alle projecten van dit programma

T-TRIPP: Tools for Translation of Risk research into Policies & Practices

How can we make sure that the (regulatory) risk research in the STW program results in knowledge and tools that can be applied both in policies and...

Project nummer: 
15809
Deelnemende kennisinstellingen: 
Koninklijke Nederlandse Akademie van Wetenschappen
Begindatum:
01-09-2017
, einddatum:
01-09-2021

Transmission of Antimicrobial Resistance Genes and Engineered DNA from Transgenic Biosystems in Nature

Microbial cell factories are used at large scale for the production of drugs, food and chemicals. Classically, such organisms were engineered by ge...

Project nummer: 
15812
Deelnemende kennisinstellingen: 
Universiteit Leiden
Begindatum:
01-08-2017
, einddatum:
31-08-2021

Towards safe applications of CRISPR/Cas9 technology in fungi

This project aims to develop efficient protocols for CRISPR/Cas9 technology in fungi and to evaluate the efficiency of this technology for differen...

Project nummer: 
15807
Deelnemende kennisinstellingen: 
Koninklijke Nederlandse Akademie van Wetenschappen
Begindatum:
01-06-2017
, einddatum:
31-05-2021

Specificity and side-effects of mutagenesis by nuclease-induced breaks and Cas9-mediated epigenome editing in plants; identifying hazards, analyzing risks and creating inherent safety.

The project will analyze side effects that can occur during or after the application of modern site specific nucleases (such as the CRISPR/Cas tech...

Project nummer: 
15792
Deelnemende kennisinstellingen: 
Wageningen Universiteit en Researchcentrum
Begindatum:
01-08-2017
, einddatum:
31-07-2021

SafeChassis: Implementing and Assessing Safeguards for Lifestyle Engineering of a Versatile Industrial Chassis

Biological engineers are developing increasingly sophisticated technical measures intended to mitigate environmental, safety and security effects o...

Project nummer: 
15814
Deelnemende kennisinstellingen: 
Wageningen Universiteit en Researchcentrum
Begindatum:
01-09-2017
, einddatum:
31-08-2019

Protein DOMINO: Amyloid exposure and associated risks

Amyloids are increasingly used as a nanomaterial in food and technological applications. Recent publications have shown indications for a prion-lik...

Project nummer: 
15784
Deelnemende kennisinstellingen: 
Universiteit Twente
Begindatum:
01-07-2017
, einddatum:
30-06-2021

Environmental safety of synthetic replicon particle vaccines – risk for RNA recombination with wildtype viruses (RepliSAFE)

Vaccines are essential tools to control infectious disease outbreaks in humans, companion animals and livestock farming animals. Next generation va...

Project nummer: 
15791
Deelnemende kennisinstellingen: 
Wageningen Universiteit en Researchcentrum
Begindatum:
03-07-2017
, einddatum:
03-07-2021

Biosafety of novel gene editing systems

The recent development of customizable and highly efficient gene editing systems, such as CRISPR/Cas9, are revolutionizing research, medicine and a...

Project nummer: 
15804
Deelnemende kennisinstellingen: 
Koninklijke Nederlandse Akademie van Wetenschappen
Begindatum:
01-07-2017
, einddatum:
30-06-2021

Assessing safety-by-design in novel plant breeding techniques by comparing native gene based modification with classical breeding

Novel plant breeding techniques (NBPTs) enable a wealth of approaches to tailor crop plants to the farmers’ and consumers’ wishes. Curr...

Project nummer: 
15815
Deelnemende kennisinstellingen: 
Wageningen Universiteit en Researchcentrum
Begindatum:
01-06-2017
, einddatum:
01-06-2021

Environmental safety evaluation of host range-modified oncolytic viruses: pivotal studies on reovirus and Newcastle disease virus

Viro-immunotherapy is a promising approach in cancer therapy in which genetically modified oncolytic viruses (OVs) are administered to patients wit...

Project nummer: 
15414
Deelnemende kennisinstellingen: 
Erasmus Universiteit Rotterdam
Begindatum:
01-02-2017
, einddatum:
31-01-2022
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