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Partnership NWO-domein TTW-Nutricia

The World Health Organization (WHO) acknowledges that the majority of priority medicines are in one way or another linked to immune- and inflammatory related disorders. Since the immune system influences the majority of physiological functions, factors that impact the immune system will have a wide range of short and long-term effects on well-being or disease manifestations throughout life.

The immune system should be “fit” in order to deal with and recover from the many challenges it faces. The newly introduced term “Immune Fitness” refers to a resilient immune system with an inbuilt capacity to adapt to challenges by establishing, maintaining and regulating an appropriate immune response. One of the important tasks of the immune system is the ability to distinguish “good” from bad: eliminate harmful agents, such as bacteria or viruses, but tolerate harmless ones, such as food.

This immune response should be of optimal strength: neither too weak (hypo-responsive) which will increase the risk of infections, nor too strong (hyper-responsive) potentially resulting in allergy, chronic inflammation or auto-immunity.

The Partnership programme NWO Domain TTW – Nutricia focusses on the development and understanding of “New concepts for specialized nutrition that influence immune fitness”, especially infant and medical nutrition.

Call text
You will be able to find more information on the Partnership “New concepts for specialized nutrition that influence Immune Fitness”, through the following link:

Call text (including appendices)
Appendix 3: Partnership Project Agreement

Financieringsinstrument 
Doel 
The objective of this Partnership programme is to stimulate translational research in immune fitness: from scientific, mechanistic ideas, to nutritional concepts that influence immune fitness, to benefits in specific health areas, in other words, from ingredients to the (proof of concept) pilot trials in humans. We invite scientists from universities and university medical centres to submit dedicated proposals aligned with the scope of the programme that may provide answers to the scientific and technological challenges described in the brochure of this call.
Contactpersoon  
Bekijk alle projecten van dit programma

Cereal fibre to improve immune function in elderly

Elderly and hospitalised persons often show a reduced activity of their immune system making them more vulnerable for infections like pneumonia tha...

Project nummer: 
16515
Deelnemende kennisinstellingen: 
Wageningen Universiteit
Begindatum:
01-06-2018
, einddatum:
01-06-2022

Local Responses to Food Allergens in Eosinophilic Esophagitis: defining mechanisms to improve diagnosis and (dietary) management

Eosinophilic esophagitis (EoE) is a chronic upper gastrointestinal allergic disease. EoE is characterized by an eosinophilic inflammation of the es...

Project nummer: 
16495
Deelnemende kennisinstellingen: 
Universiteit van Amsterdam
Gebruikers: 
One other company is involved in this project.
Begindatum:
01-06-2018
, einddatum:
01-06-2022

Maternal immune activation during pregnancy – a dietary intervention to restore immune fitness in the offspring

The first 1000 days of life are the most critical period of development. Environmental exposures during pregnancy, such as infection, may disrupt i...

Project nummer: 
16518
Deelnemende kennisinstellingen: 
Universiteit Utrecht
Begindatum:
01-06-2018
, einddatum:
01-06-2022

EARLYFIT

This project group will investigate the effect of infant formula with synbiotics on immune fitness. Synbiotics are a combination of pre- and pro-bi...

Project nummer: 
16490
Deelnemende kennisinstellingen: 
Wageningen Universiteit
Begindatum:
01-06-2018
, einddatum:
01-06-2022
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